Trevor Lawrence finally suffered an injury he can't play through, with the Jaguars officially ruling him out for Week 17.
Already thin at wide receiver, the Saints can only hope Chris Olave gains clearance from an independent neurologist Friday night or Saturday.
After two years of uneven quarterback play, the Saints are banking on Derek Carr to right the ship on offense. He'll have plenty of talent to work with, namely RB Alvin Kamara and WR Chris Olave, among others.
Erik Siegrist analyzes the Monday night matchup as Tom Brady and the Bucs take on the Saints in a key NFC South showdown.
Erik Siegrist previews the Monday night matchup as Jonathan Taylor and the Colts take on the visiting Steelers.
Keenan Allen and Mike Williams both expect to play this week, while the Chiefs are hurting at wide receiver and the Saints and Bills appear thin on defense.
Erik Siegrist previews the Monday night game as Jimmy Garoppolo and the 49ers face the division-rival Cardinals in Mexico City.
Kyler Murray is one of four starting quarterbacks listed as questionable, while Jonathan Taylor, Aaron Jones, Elijah Mitchell and Kyren Williams all got the green light Friday.
Erik Siegrist previews the Monday night matchup as Jalen Hurts and the Eagles play host to Washington.
Erik Siegrist analyzes the Monday night matchup as Lamar Jackson and the Ravens travel to New Orleans.
Following Sean Payton's retirement, the Saints may not experience much change in philosophy, considering the offensive coordinator is a holdover and the impending returns of Michael Thomas and Jameis Winston.
Erik Siegrist previews the Monday night matchup with game predictions, fantasy projections and DFS picks as Ben Roethlisberger and the Steelers try to keep their playoff hopes alive against the Browns.
Erik Siegrist previews the Monday night matchup with game predictions, fantasy projections and DFS picks, as Jameis Winston and the Saints face the host Seahawks.
Erik Siegrist previews the Monday night matchup as the Colts visit the Ravens.
Erik Siegrist previews the Monday night matchup as Justin Herbert and the Chargers take on the Raiders in a key AFC West showdown.
Erik Siegrist previews the Monday night game as Dak Prescott and the Cowboys play host to the division-rival Eagles.
Erik Siegrist previews the Monday Night Football matchup as Aaron Rodgers and the Packers look to bounce back against the Lions.
The Saints never fully capitalized on the twilight of Drew Brees' career. With the QB moving on to retired life, the offense will begin the year without Michael Thomas, setting up Alvin Kamara to feast.