1.  
Rush Att
252
Rush Yds
1126
Rush TD
10
Rush Avg
4.5
Rec
88
Rec Yds
767
Rec TD
4
Rec Avg
8.7
After not missing a game through his first three NFL seasons and seeing heavy workloads in the last two, McCaffrey signed a big contract extension last summer and promptly broke down. Ankle, shoulder and thigh injuries limited him to only three weeks of action in 2020, and while he scored six touchdowns in those three contests and was still his usual electric self when he was on the field, it was not what Carolina expected when it made him the highest-paid running back in the league. When he's in top form, McCaffrey is an elite pass-catching option out of the backfield who is tough for defenders to get their hands on in the open field, and new head coach Matt Rhule showed no hesitation in using his superstar at the goal line, as all six of McCaffrey's TDs came from inside the 10-yard line. His per-game workload was essentially the same as his usage under the previous regime, and none of last year's injuries appear to be long-term concerns. The Panthers also did little to add backfield depth apart from fourth-round pick Chuba Hubbard, a strong indication McCaffrey will once again handle the type of role that could lead to 400-plus touches if he plays 15 or 16 games.
2.  
RB  IND
Rush Att
280
Rush Yds
1367
Rush TD
13
Rush Avg
4.9
Rec
48
Rec Yds
417
Rec TD
2
Rec Avg
8.7
When Marlon Mack ruptured his Achilles in Week 1 it was assumed Taylor would immediately erupt, and while the rookie did post his first 100-yard rushing game in Week 2, it took him a while to get going after that. Between Weeks 3 and 10, he failed to top 68 yards as he adjusted to the NFL, but down the stretch Taylor broke through and became the player Indianapolis thought it was drafting in the second round. Over his final six regular-season games, Taylor amassed 741 rushing yards and seven TDs, including a mammoth 253 yards and two scores in Week 17 to help the Colts lock up a playoff spot. The 22-year-old has an enviable blend of power, speed and agility, and he showed good patience in waiting for Indy's elite offensive line to open holes that would allow him to explode into the second level. Taylor isn't a natural pass catcher, but he's adequate in that area, and with Nyheim Hines on the roster he won't have to handle the bulk of those duties. Mack also signed a one-year deal to return and provide some insurance, but after the way Taylor closed out 2020, it's hard to see him working in any kind of committee. He hasn't yet reached his ceiling, and more work at the goal line (he barely saw half of the Colts' red-zone carries, a rate well behind the likes of Josh Jacobs or Ezekiel Elliott) could push his production into the stratosphere.
3.  
RB  MIN
Rush Att
290
Rush Yds
1366
Rush TD
12
Rush Avg
4.7
Rec
56
Rec Yds
477
Rec TD
2
Rec Avg
8.5
Cook once again did not suit up for a full schedule, missing Week 6 last year with a minor groin strain before leaving the team in Week 17 after the death of his father, but his production when he was on the field was phenomenal. He finished second in the league in rushing yards and rushing TDs, behind only Derrick Henry, and no back saw more carries inside the five-yard line or broke more tackles than Cook. His combination of strength, elusiveness and breakaway speed makes him perhaps the most dangerous pure runner in the NFL, and while Cook doesn't have the route-running ability of some other three-down backs, he's recorded at least 40 receptions in three consecutive seasons, proving capable as a pass catcher. The circumstances around him remain extremely favorable as well. The offensive line figures to get better with Ezra Cleveland and Garrett Bradbury solidifying the middle, while coach Mike Zimmer is still predisposed to a ground-and-pound gameplan. New offensive coordinator Klint Kubiak did come up through the ranks focused on the passing game, but his father Gary was no stranger to dominant rushing attacks during his coaching career. One of these years Cook is going to play 16 games, and 2,000-plus scrimmage yards likely will follow.
4.  
RB  TEN
Rush Att
330
Rush Yds
1523
Rush TD
15
Rush Avg
4.6
Rec
17
Rec Yds
118
Rec TD
1
Rec Avg
6.9
It's still mind-boggling that as recently as 2018, the Titans thought Henry needed to split touches with Dion Lewis. Since then, he's proven to be the most physically dominant back in the league, winning consecutive rushing crowns and posting the eighth 2,000-yard campaign in NFL history. Henry hasn't wilted as his carries have increased either, keeping his YPC higher than 5.0 for the second straight season and finishing second to Dalvin Cook in broken tackles. In fact, Henry seems to thrive on dishing out punishment to defenders, and if you only counted his yards after contact, he still would have finished fourth in the league in rushing. There's just nothing subtle about his running style, as he uses his 6-3, 247-pound frame to bludgeon his way through holes and over would-be tacklers, while his nimble feet and breakaway speed are what set him apart from large backs who get stuck in short-yardage roles. The Titans will look for 2020 third-round pick Darrynton Evans to take a step forward and become a reliable passing-down option, but there's little else on the depth chart behind the duo as the team has clearly learned its lesson. Henry should once again see a big workload, pound out yards and wear down defenses, allowing Ryan Tannehill to do damage off play-action.
5.  
RB  CLE
Rush Att
299
Rush Yds
1428
Rush TD
12
Rush Avg
4.8
Rec
31
Rec Yds
271
Rec TD
1
Rec Avg
8.7
A knee injury cost Chubb four games in the first half of 2020, but even if he had been healthy for all 16 contests, a timeshare with Kareem Hunt would have prevented him from matching his 2019 volume or production. It's hard to argue with the results on an efficiency basis, though, as Chubb set a career high with 5.6 YPC, and his 25.3 percent broken tackle rate led all backs with at least 100 totes. The 25-year-old combines elite speed with power and agility, allowing him to run around or through would-be tacklers with equal skill, and while he didn't get used much in that area last year, he's also a capable pass catcher. When both backs were healthy, Chubb was Cleveland's top option last season, averaging 17.2 touches to Hunt's 13.4 in the 12 games they played together. That's still not the kind of volume enjoyed by RBs around the league who have a backfield to themselves, but it wouldn't take much of a shift in that distribution to get Chubb to 300 touches over a full season. With the Browns finally looking like a serious contender, coach Kevin Stefanski won’t deviate too much from a successful formula. Chubb's upside running behind one of the NFL's best offensive lines would be massive should he find himself with a bigger workload, and his floor in the Browns' current arrangement is secure.
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