Jamaal Williams hasn't done much for the Saints this year but may now be forced into a huge role Week 18 against the Falcons.
Khalil Herbert re-emerged as Chicago's lead runner Week 16 and went over 100 yards, but his role moving forward may (or may not) depend on D'Onta Foreman's availability.
Ty Chandler's impressive Week 15 performance could keep him in the lead role even if Alexander Mattison returns from an ankle injury soon.
Chicago's D'Onta Foreman retook the the lead role -- ahead of Khalil Herbert and Roschon Johnson -- in his first game back from an ankle injury.
Five starting RBs left Week 13 contests early, potentially setting up lead roles for Ezekiel Elliott, Kenneth Gainwell and others. Meanwhile, Chuba Hubbard and James Conner topped 100 yards and scored twice.
Roschon Johnson took over the lead role Monday night, but it's unclear if that will hold after a Week 13 bye.
AJ Dillon struggled in a lead role earlier this season, but he's played better recently and now gets another chance to replace an injured Aaron Jones as Green Bay's starting running back.
Jameson Williams hadn't done much with increased playing time the past two weeks before catching a TD late in the fourth quarter against Chicago this past Sunday. Is there still hope?
Juan Carlos Blanco surveys the extremely busy Week 11 Sunday morning injury landscape and dishes the latest news on the potential availability of multiple big fantasy names.
Will the Chiefs' offense get their mojo back after the bye week against the Eagles?
Devin Singletary's huge game in Cincinnati may have been enough to displace Dameon Pierce from the starting role once he returns from an ankle injury.
Steelers RB Jaylen Warren had a season-high for carries for the second straight week and topped 50 percent snap share for the first time all season.
Juan Carlos Blanco has a Sunday morning update on a Week 10 injury report containing some big fantasy names.
Keaton Mitchell is a tough player to rank this week because of the Ravens' timeshare at RB and the tough opponent this week.
Aaron Jones finally got back to a high-usage role after nearly two months of being held back by a hamstring injury.
Juan Carlos Blanco has the latest as of Sunday morning on a Week 9 injury report heavily populated by the quarterback position.
Chuba Hubbard dominated Carolina's backfield work even with Miles Sanders back in the lineup, and Denver's Javonte Williams returned to a workhorse role against the Chiefs.
Can A.J. Brown keep it rolling in a showdown against the tough Cowboys defense?