Leeds are back in action which means Raphinha will be a popular play, especially at home against Burnley for Sunday's three-game slate at DraftKings.
Harry Kane has a goal in each of the last three matches and has a good chance to add another, as he leads the FPL rankings in Gameweek 21 for a trip to Watford.
Michail Antonio has made the scoresheet in back-to-back matches and will hope to make it a third in a decent matchup against Crystal Palace for Gameweek 21.
Liverpool are away from home at West Ham, but once again, goals are expected from the Reds with Mohamed Salah and Sadio Mane being two of the best Fantrax options for Gameweek 11.
Chelsea are dealing with injuries, but they have the best chance for a clean sheet at home against Burnley in Gameweek 11 and their defenders top the FPL rankings.
Mohamed Salah continues to be an elite fantasy scorer, and RotoWire's Andrew Laird is expecting the Liverpool superstar to make a big impact this weekend against Leeds United.
Jamie Vardy continues to lead the line for Leicester City, but a tough matchup this weekend has him low in Andrew Laird's weekly Fantasy Premier League player rankings.
Even though his goal upside took a hit with Manchester United's addition of Cristiano Ronaldo, RotoWire's Andrew Laird is still expecting a big season from Bruno Fernandes.
With the transfer window finally closed, RotoWire's Andrew Laird breaks down his full player rankings for the 2021/22 Premier League season.
With a Champions League spot on the line, RotoWire's Andrew Laird is expecting Mohamed Salah to have a major impact in Liverpool's Premier League finale against Crystal Palace.
RotoWire's Andrew Laird is expecting Liverpool to take care of business Sunday against Crystal Palace, which is why plenty of Reds are near the top of his weekly player rankings.
The Manchester City attack hasn't been as dominant, but RotoWire's Andrew Laird is still expecting Kevin De Bruyne to have a big impact against Everton this week.
Tottenham have gone four straight games without scoring multiple goals, but RotoWire's Andrew Laird is expecting them to break their streak this week against Fulham.
Fantasy players should expect plenty of rotation due to the condensed holiday schedule, including the potential return of Sergio Aguero at the top of the Manchester City attack for Gameweek 16.
Diogo Jota was rested for Wednesday's Champions League match against Atalanta, but he could slot back into the lineup for Saturday's match against Brighton.
Bruno Fernandes has been the focal point of the Manchester United attack, and RotoWire's Schuyler Redpath is expecting the midfielder to have another strong game Tuesday against Istanbul Basakeshir.
Chelsea are expected to take care of business away to Newcastle this weekend, which is why many Blues are high in Andrew Laird's weekly player rankings.